Oncospace

K242748

Oncospace, Inc. · cleared 2025-04-11 · product code MUJ · Radiology

Premarket evidence — what FDA accepted

Device typesamd
source quote (p.7)
The Oncospace subject device is a software-only medical device that performs the same functions as the Oncospace predicate device. The following verification and validation testing results (performance data) support the substantial equivalence determination. Since this is a software-only medical device that does not control other devices the performance data does not include biocompatibility, electrical safety, electromagnetic compatibility, mechanical, acoustic, or animal testing.
AlgorithmThe software includes locked machine learning algorithms. The Oncospace software includes an algorithm for transforming non-standardized OAR names used by treatment planners to standardized names defined by AAPM Task Group 263. This matching process primarily uses a table of synonyms that is updated as matches are made during use of the product, as well as a Natural Language Processing (NLP) model that attempts to match plan names not already in the synonym table.
source quote (p.5)
The software includes locked machine learning algorithms. The Oncospace software includes an algorithm for transforming non-standardized OAR names used by treatment planners to standardized names defined by AAPM Task Group 263. This matching process primarily uses a table of synonyms that is updated as matches are made during use of the product, as well as a Natural Language Processing (NLP) model that attempts to match plan names not already in the synonym table.
Adaptive (vs locked)No
source quote (p.5)
The software includes locked machine learning algorithms. Note: The subject device algorithms, and any future algorithm updates, are locked prior to clinical use.
PCCPFDA source did not state this
Cybersecurity addressedYes
source quote (p.10)
The verification tests met all system requirements and acceptance criteria which address clinical, standard user interface, and cybersecurity requirements for the Oncospace device.

Validation studies (5)

Retrospective clinical

n=18 patients · 1 site(s)

endpoints: plan quality as represented by mean organ-at-risk (OAR) dose sparing; target coverage

Retrospective clinical

n=20 patients · 1 site(s)

endpoints: plan quality as represented by mean organ-at-risk (OAR) dose sparing; target coverage

Retrospective clinical

n=17 patients · 1 site(s)

endpoints: plan quality as represented by mean organ-at-risk (OAR) dose sparing; target coverage

Retrospective clinical

n=17 patients · 1 site(s)

endpoints: plan quality as represented by mean organ-at-risk (OAR) dose sparing; target coverage

Standalone

n=221 other

endpoints: macro-averaged F1 score; accuracy; correctly matched structure names

Reported performance (2 observations)

f1as written: “NLP model validation macro-averaged F1 score0.92CI above 0.92
source quote (p.13)
During 5-fold cross-validation all models achieved a validation macro-averaged F1 score above 0.92
accuracyas written: “NLP model validation accuracy0.96CI above 96%
source quote (p.13)
and accuracy above 96% for classifying previously unseen terms.

Each value carries its own analysis unit and task — never compare or pool across devices. Source: 510(k) summary PDF.

Predicate network

Postmarket — what happened after clearance

35
recalls in product code, 24mo
17
MAUDE reports in code, 12mo
-50%
vs code's own 3-yr baseline
2
drift signals on this device
  • recall_reason_pattern

    Software/algorithm-related recall in product code MUJ (Philips Medical Systems (Cleveland) Inc, initiated 2025-08-05): "Due to a software issue, there is a potential image error of the Region of Interest for expansion/contraction for HFP (Head First Prone), FFS (Feet First Supine) and FFP (Feet Firs" Recalling firm is another firm in the same product code.

    first seen 2026-07-08 · recall res_event_number:97049

  • recall_reason_pattern

    Software/algorithm-related recall in product code MUJ (Philips Medical Systems (Cleveland) Inc, initiated 2025-07-17): "Due to software issue, Radiation Therapy Planning system may provide incorrect dataset calculations when performing the "Stopping Power Ratio" (SPR) ," Recalling firm is another firm in the same product code.

    first seen 2026-07-08 · recall res_event_number:97309

Recall and MAUDE counts are product-code-level (reports aren't reliably attributable to one device). Signals are descriptive observables with sources — never a judgment that the device is unsafe or drifting. Snapshot 2026-07-08.

Reimbursement — how devices like this got paid

Not yet tracked — no payment pathway indexed for this clearance (the reimbursement corpus is a growing seed set).

RIGOR™ Precedent · public FDA/CMS data · descriptive decision-support, not regulatory or reimbursement advice. Share this page: radar.healthai.com/precedent/device/K242748