BoneMRI

“The BoneMRI application is a standalone image processing software application that analyses 3D gradient echo MRI scans acquired with a dedicated MRI scan protocol.”

“MRIguidance software implements an image enhancement algorithm using convolutional neural network. Original images are enhanced by running them through a cascade of filter banks, where thresholding and scaling operations are applied. Separate neural network-based filters are obtained to assign a Hounsfield Unit (HU) value to a single volume element, based on intensity and contextual information. The parameters of the model were obtained through an algorithm development pipeline.”

“In accordance with the PCCP, all algorithm modifications will be trained, tuned, and locked prior to release of the application.”

“Addition of a Predetermined Change Control Plan to support an iterative development approach for the machine learning models in the BoneMRI application.”

“The BoneMRI application is a server application running on the clinic or hospital networks. It is available as fully on-premise software with specific GPU hardware requirements, or partly running as a managed cloud service, for which the environment in which the managed modules run is controlled by MRIguidance. The on-premise software is fully controlled by the clinic or hospital, and as such, no protected health information (PHI) will leave the clinic or hospital network. All data sent to the managed cloud server will be de-identified before it leaves the clinic or hospital network, and as such, the managed cloud service will not receive PHI.”