Lunit INSIGHT MMG

K211678

Lunit Inc. · cleared 2021-11-17 · product code QDQ · Radiology

Premarket evidence — what FDA accepted

Device typesamd
source quote (p.5)
Lunit INSIGHT MMG is a radiological Computer-Assisted Detection and Diagnosis (CADe/x) software for aiding interpreting physicians with the detection, localization, and characterization of suspicious areas for breast cancer on mammograms from compatible FFDM (full-field digital mammography) systems. The software applies an artificial intelligence algorithm for recognition of suspicious lesions, which are trained with large databases of biopsy proven examples of breast cancer, benign lesions and normal tissues. and Software-only device
Algorithmartificial intelligence algorithm, deep learning algorithm, machine learning techniques
source quote (p.5)
The software applies an artificial intelligence algorithm for recognition of suspicious lesions, which are trained with large databases of biopsy proven examples of breast cancer, benign lesions and normal tissues. and In Lunit INSIGHT MMG, a range of medical image processing and machine learning techniques are implemented. The system includes 'deep learning' algorithm applied to images for recognition of suspicious lesions for breast cancer. The machine learning components are trained to detect suspicious lesions for breast cancer with large databases of biopsy-proven cases of breast cancer, benign lesions and normal tissues.
Adaptive (vs locked)No
source quote (p.5)
The software applies an artificial intelligence algorithm for recognition of suspicious lesions, which are trained with large databases of biopsy proven examples of breast cancer, benign lesions and normal tissues.
PCCPFDA source did not state this
Cybersecurity addressedFDA source did not state this

Validation studies (2)

Standalone

n=2,412 images

endpoints: ROC AUC; LROC AUC; sensitivity; specificity

Reader study (MRMC)

n=240 cases

endpoints: diagnostic ability of radiologist with CAD assistance is superior to without CAD assistance; FBR (Forced BI-RADS) ROC AUC between reader's interpretation and device-assisted interpretation for the detection of malignant lesions; inter-test difference in LCM (level of confidence of malignancy) LROC AUC; LCM ROC AUC; recall rate in cancer and non-cancer group (sensitivity and 1-specificity)

Reported performance (12 observations)

sensitivity85.74CI [82.95, 88.53]
source quote (p.8)
Sensitivity (%) [95% CI] 85.74 [82.95, 88.53]
specificity75.62CI [73.64, 77.60]
source quote (p.8)
Specificity (%) [95% CI] 75.62 [73.64, 77.60]
aurocas written: “auc0.903CI [0.889, 0.917]
source quote (p.8)
ROC AUC [95% CI] 0.903 [0.889, 0.917]
aurocas written: “Type I LROC AUC0.781CI [0.751, 0.812]
source quote (p.8)
Type I LROC AUC [95% CI] 0.781 [0.751, 0.812]
aurocas written: “Type II LROC AUC0.792CI [0.763, 0.822]
source quote (p.8)
Type II LROC AUC [95% CI] 0.792 [0.763, 0.822]
aurocas written: “ROC AUC (unaided)0.754CI (0.702, 0.807)
source quote (p.9)
ROC AUC (95%CI) 0.754 (0.702, 0.807)
aurocas written: “ROC AUC (aided)0.805CI (0.759, 0.852)
source quote (p.9)
ROC AUC (95%CI) 0.805 (0.759, 0.852)
aurocas written: “ROC AUC difference (Test2-Test1)0.051CI (0.027, 0.075)
source quote (p.9)
Test2-Test1 0.051 (0.027, 0.075)
aurocas written: “LCM ROC AUC0.052CI 0.026 - 0.079
source quote (p.9)
LCM ROC AUC 0.052 (95% CI: 0.026 - 0.079)
sensitivityas written: “recall rate in cancer group (sensitivity)5.97CI 2.48 - 9.46
source quote (p.9)
recall rate in cancer group (sensitivity) 5.97(95% CI: 2.48 - 9.46)
sensitivityas written: “recall rate in non-cancer group (1-specificity)-1.46CI -3.41 - 0.05
source quote (p.9)
recall rate in non-cancer group (1-specificity) -1.46 (95% CI: -3.41 - 0.05)
aurocas written: “ROC AUC (standalone algorithm performance with reader study cases)0.863CI 0.818 - 0.909
source quote (p.9)
ROC AUC in the standalone performance analysis is 0.863 (95% CI: 0.818 - 0.909)

Each value carries its own analysis unit and task — never compare or pool across devices. Source: 510(k) summary PDF.

Predicate network

Postmarket — what happened after clearance

0
recalls in product code, 24mo
0
MAUDE reports in code, 12mo
vs code's own 3-yr baseline
0
drift signals on this device

Recall and MAUDE counts are product-code-level (reports aren't reliably attributable to one device). Signals are descriptive observables with sources — never a judgment that the device is unsafe or drifting. Snapshot 2026-07-08.

Reimbursement — how devices like this got paid

Not yet tracked — no payment pathway indexed for this clearance (the reimbursement corpus is a growing seed set).

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